Pregnancy and helminth infections

Pregnancy and helminth infections

It has been proposed that helminth infection may be particularly detrimental during pregnancy, through adverse effects on maternal anaemia and on birth outcomes, and that anthelminthic treatment during pregnancy will therefore be particularly beneficial. However, the few treatment trials that have been conducted have given, but little support to this notion and further trials in settings of nut...

Malnutrition and parasitic helminth infections.

The Global Burden of Disease caused by the 3 major intestinal nematodes is an estimated 22.1 million disability-adjusted life-years (DALYs) lost for hookworm, 10.5 million for Ascaris lumbricoides, 6.4 million for Trichuris trichiura, and 39.0 million for the three infections combined (as compared with malaria at 35.7 million) (World Bank, 1993; Chan et al. 1994); these figures illustrate why s...

Maternal helminth infections.

© Springer Science+Business Media New York 2014 W. Horsnell (ed.), How Helminths Alter Immunity to Infection, Advances in Experimental Medicine and Biology 828, DOI 10.1007/978-1-4939-1489-0_2 C. Prazeres da Costa () · K. Straubinger Department of Parasitology, Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Trogerstrasse 30, 81675 Munich, Germany e-m...

Vaccination against helminth parasite infections.

Helminth parasites infect over one fourth of the human population and are highly prevalent in livestock worldwide. In model systems, parasites are strongly immunomodulatory, but the immune system can be driven to expel them by prior vaccination. However, no vaccines are currently available for human use. Recent advances in vaccination with recombinant helminth antigens have been successful agai...

Helminth infections: Domestic ruminants: Introduction